University of Toronto



Department of Laboratory Medicine and Pathobiology
Faculty of Medicine, University of Toronto
Medical Sciences Building, 1 King’s College Circle
Toronto, ON, Canada M5G 1L5


Paul M. Yip, PhD, FCACB, DABCC
Vathany Kulasingam, PhD, FCACB
Telephone: (416) 978-7535
Fax: (416) 978-731
Emails: | |


Affiliated Institutions

Mount Sinai Hospital
University Health Network
The Hospital for Sick Children
Sunnybrook Health Science Centre
St. Michael’s Hospital and St. Joseph Health Science Centre

Faculty and Training/Research Interests

University Health Network
Vathany Kulasingam, PhD, FCACBImmunoassays, immunosuppressive drugs, endocrinology
Davor Brinc, PhD, FCACBRoutine and special chemistry; outreach programs
Rajeevan Selvaratnam, PhD, DABCCSTAT and automated chemistry; immunoassays
Hospital for Sick Children
Khosrow Adeli, PhD, FCACB, DABCCPediatric clinical chemistry, reference intervals, research projects
Benjamin Jung, PhD, FCACBPharmacology, pharmacogenetics, TDM, toxicology
Lusia Sepiashvili, PhD, FCACBSpecial chemistry, immunology, routine chemistry
Lipin Yuan, PhD, ABMGMetabolic disease, inborn errors of metabolism, glycosylation defects
Mount Sinai Hospital
Eleftherios Diamandis, MD, PhD, FCACBDiagnostic and prognostic approaches to breast and prostate cancer, proteomics, mass spectrometry
Barry Hoffman, PhD, FCACBMaternal serum screening program
Felix Leung, PhDGeneral and special chemistry, quality assurance
Jennifer Taher, PhDSTAT and routine chemistry, special chemistry
Sunnybrook Health Science Centre
Paul Yip, PhD, FCACB, DABCCCardiac markers, quality assurance, point-of-care testing
P.C. Chan, PhD, FCACBProtein abnormalities, multiple myeolma, cancer
David E.C. Cole, MD, FRCPCMolecular diagnosis, homocystine metabolism, metabolic bone disease
Lei Fu, PhD, FCACBPregnancy, prenatal disorders, pediatrics
St. Michael’s Hospital and St. Joseph Health Centre
Maria Pasic, PhD, FCACBRoutine and special chemistry
Daniel Beriault, PhD, FCACBSpecial chemistry, toxicology

Program Listing:

Level(s) of training: Postdoctoral
Number of position available per year: 2
Duration of program: 2 years
Approximate annual salary or stipend: $60,000
Source of funding: Ontario Ministry of Health and University of Toronto
Current number of trainees: 4
Number of past graduates: 125 (1968 to present)

Application Procedures:


PhD in biochemistry or a related science; Canadian citizenship or landed immigrant status; good communication skills; strong background in biochemistry/chemistry, physiology; good research record


Submit completed Fellowship Application form, curriculum vitae, official transcripts, and completed referee forms and letters of reference from three referees. Interview required.


January 15th of the year prior to start of training (July 1)

Program Description

The training program in clinical chemistry, established in 1968, is the largest in Canada and accepts 2 candidates each year. Currently, there are 4 fellows in the program (2 first year, 2 second year).

The program is 2 years in duration. Courses taken by candidates include clinical biochemistry, analytical clinical chemistry, techniques in functional genomics & proteomics, metabolism & nutrition, epidemiology and statistics, and management. Teaching methods used include didactic, directed reading, resident presentations, seminars, case-oriented teaching, and practical exercises.

The first-year hospital rotation is based on a laboratory rotation guide which has been published and which provides direction for the learning experience in the analytical and clinical aspects of the profession. Molecular biology is included in the first year of training. Training in the second year includes specialty rotations in pediatrics & toxicology, genetic metabolic laboratory, microbiology, hematology, GC-MS/Tandem MS, and microarrays/sequencing.

All residents are required to carry out at least 3 projects in the area of diagnostic test development, and participate in rounds and seminars, case presentation and journal club sessions, weekly discussions with faculty, investigation and approval of unusual tests, teaching, and elective periods for specialization, or applied or basic research.