National Institutes of Health



Department of Laboratory Medicine
10 Center Drive, Building 10, Room 2C306
Bethesda, MD  20892-1508


David B. Sacks, MB, ChB
Telephone:  301-496-3386
Fax:  301-402-1885

Associate Director

Roa Harb, MD
Telephone:  301-496-3386
Fax:  301-402-1885

Faculty and Research Interests

National Institutes of Health (NIH)

David B. Sacks, MB, ChBHbA1c, Glucose, Biomarkers of diabetes, Intracellular signal transduction
Alan Remaley, MD, PhDLipoprotein metabolism, Atherosclerosis, Cardiovascular biomarkers
Steven J. Soldin, PhDPharmacology, drug and metabolite studies, Endocrinology, HPLC, Mass Spectrometry, New test development for steroids, thyroid hormones and peptides, Evaluation of these tests in clinically approved protocols
Roa Harb, MDGlobal Health, General Chemistry, Endocrinology, Test Utlilization
Karen M. Frank MD, PhDClinical Microbiology
Jay Lozier MD, PhDHematology
Boris Calderon, MDClinical Chemistry, Immunoassays, Autoimmune testing, Biomarker development

Children’s National Medical Center

Naomi Luban MDHematology
Edward Wong MDTransfusion Medicine
Sean E. Hofherr, PhDClinical Biochemical/Medical Genetics

Program Listing

Level(s) of training: Postdoctoral
Number of positions available per year: 1
Duration of program: 2-3 years
Approximate annual salary or stipend:
Source of funding: NIH Postdoctoral Intramural Research Training Award (IRTA)
Current number of trainees: 2
Number of past graduates: 12 trainees in the period 1999-2016

Application Procedures


Qualified candidates who have completed a Ph.D. and/or M.D., or equivalent degree from a recognized institution of higher learning. Applicants must have satisfactorily completed a minimum of 30 semester hours in undergraduate and/or graduate level chemistry or biochemistry courses prior to admission into the program to meet certification eligibility requirements by the American Board of Clinical Chemistry.


Submit letter of interest, curriculum vitae, and three letters of reference. Interview required.


October 1st  for positions commencing July 1st of the following year

Program Description

The objectives of the clinical chemistry fellowship program in the Department of Laboratory Medicine at the NIH are to train individuals to manage high complexity laboratories, to become clinically oriented and participate in a variety of largely translational research projects, to develop their own research foci and to cover the set curriculum of ComACC, thereby ensuring successful examination outcomes. The training emphasizes the clinical aspects of clinical chemistry, with active participation by the fellows via an on-call system.

Trainees will be expected to have a comprehensive knowledge of, and skills in:

  • Biochemistry, physiology, general and special pathology
  • The biochemical and metabolic basis of disease
  • The application of laboratory test results to the investigation and management of patients
  • The investigation of clinical and laboratory problems
  • The provision of specialist opinion in clinical chemistry
  • Accreditation theory and practice
  • Physical and chemical principles of analytical techniques and analytical methods
  • Method and platform evaluation
  • Efficient laboratory administration and management skills to provide an effective service
  • Data management and computational skills and knowledge
  • Health and Safety requirements for laboratories
  • The processes required to conduct research, namely reviewing the literature, writing scientific proposals, writing ethics and grant applications
  • Participation in current translational research projects, and development of their own research foci