Johns Hopkins Medical Institutions



Department of Pathology, Meyer B-121
Johns Hopkins Medical Institutions
1800 Orleans Street
Baltimore, MD 21287-7065


William Clarke, PhD, MBA, DABCC
Telephone: (410) 502-7692
Fax: (410) 955-0767

Mark A. Marzinke, PhD, DABCC
Telephone: (443) 287-7516
FAX: (410) 955-0767


Faculty and Research Interests

Daniel W. Chan, PhD, DABCC Cancer proteomics, tumor markers, immunoassay automation
William Clarke, PhD, DABCC Therapeutic drug monitoring, clinical toxicology, mass spectrometry assay development
Barbara Detrick, PhD Immunology
Thomas Kickler, MD Hematology and Coagulation
Claire Knezevic, DABCC Critical care testing, TDM/toxicology, mass spectrometry
Mark Marzinke, PhD, DABCC Pharmacogenetics, lab automation, mass spectrometry, pharmacology, quality improvements
Ming-Tseh Lin, MD Molecular Pathology
Lori J. Sokoll, PhD Tumor markers, immunoassays
Hui Zhang, PhD Clinical proteomics, glycoproteomics, mass spectrometry
Zhen Zhang, PhD Bioinformatics, mathematical and computational algorithms

Program Listing

Level(s) of training: Postdoctoral
Number of positions available per year: 1
Duration of program: 2 years
Approximate annual salary or stipend: Commensurate with experience
Source of funding: University
Current number of trainees: 3
Number of past graduates: 17 (since 1997)

Application Procedures


Applicants must have an earned Doctor of Medicine degree or Doctor of Philosophy (or an equivalent doctoral degree) in the basic sciences; chemistry, biology or physics from an accredited university or college. Applicants should have successfully completed enough chemistry courses to apply to the American Board of Clinical Chemistry, i.e., a minimum of 30 semester hours (or equivalent) in undergraduate and/or graduate level chemistry or biochemistry courses taken at institutions acceptable to the Board


Submit a letter of intent and curriculum vitae for initial consideration. Selected applicants will be required to complete a formal application and submit transcripts and three letters of recommendation. (Johns Hopkins does not discriminate on the basis of race, color, sex, religion, homosexuality, nation or ethnic origin, age, disability, or veteran status in any student program or activity administered by the University or with regard to admission or employment.)


September 1 for position to start July 1 of the following year

Program Description

The Department of Pathology offers a one- or two-year fellowship to provide MD pathologists and PhD scientists with the analytical, clinical, research, and management experience towards specialization and board certification in clinical chemistry. The Clinical Chemistry Division performs over seven million tests each year in state-of-the-art laboratories that provide 24-hour service to The Johns Hopkins Hospital, the Bayview Medical Center , and several community outpatient facilities. The fellow rotates through routine automated chemistry (high-volume testing), critical care (blood gases, stat testing), special chemistry (immunoassay for endocrine function and tumor markers, trace metal analysis) and drug analysis (therapeutic drug monitoring and drugs of abuse testing) laboratories. The program is designed to provide training in the operation of a clinical laboratory, quality control and assurance, laboratory management, analytical methodologies and test interferences. The clinical interpretation and diagnostic relevance of tests are emphasized through clinical consults. Research projects could involve method development, test validation, and clinical and scientific investigation in any of the areas within clinical chemistry. In addition, there are opportunities to conduct translational research in the field of clinical proteomics through the Center for Biomarker Discovery at Johns Hopkins University. The structure of the program is flexible to afford individualized training based on previous experience.